Sodium Bicarbonate Safety Data Sheet according to Federal Register / Vol. It is broadly used as an physiological buffer in in vitro applications. 58 / Monday, March 26, 2012 / Rules And Regulations And According To The Hazardous Products Regulation (February 11, 2015). Pharmacotherapy 15 (1995): 660-4, 19. Br J Psychiatry 149 (1986): 502-3, 5. Excess heat. 77, No. Page 1 of 4 Chief Medical Supplies Ltd. 411 – 19 Street, S. E. Calgary, AB., Canada. The natural mineral form is nahcolite. Potential Health Hazards from Sodium Bicarbonate While sodium bicarbonate is generally not considered to be amongst the most harmful of chemicals, exposure to large amounts may result in some adverse health effects, such as: Coughing and sneezing if a … The mortality associated with gastric rupture is as high as 65%. Check with your doctor as soon as possible if any of the following side effects occur while taking sodium bicarbonate: Some side effects of sodium bicarbonate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. 8. The pKa for bicarbonate <-> carbonic acid reaction is 6.4 The pKa for bicarbonate <-> carbonate reaction is 10.3. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. SAFETY DATA SHEET. Fordtran JS, Morawski SG, Santa Ana CA, Rector FC, Jr "Gas production after reaction of sodium bicarbonate and hydrochloric acid." This site requires Javascript to be enabled for full functionality. of baking soda diluted in one glass of water every two hours. Hazard PB, Griffin JP "Sodium bicarbonate in the management of systemic acidosis." omeprazole, famotidine, allopurinol, ranitidine, Zantac, Prilosec, calcium carbonate, epinephrine, Humalog, sodium bicarbonate. Synonym: Baking Soda; Bicarbonate of soda; Sodium Take sodium bicarbonate as your doctor’s prescription instructs 2 3.The general recommendation for heartburn is 1/2 tsp. Intensive Care Med 13 (1987): 425-7, 17. P 103 / USA Issuing date 12/09/2008 / Report version 1.0 Copyright 2008, SOLVAY CHEMICALS, INC. All Rights Reserved "Product Information. Irritability and tetany have been associated with sodium bicarbonate-induced alkalosis or hypernatremia. Sodium bicarbonate is the active ingredient in baking soda. Over-the-counter antacid products containing sodium bicarbonate … Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Sigma-Aldrich offers a number of Sodium bicarbonate products. 77, No. 586 Argus Road Indian J Pediatr 45 (1978): 277-8, 16. Cooper DJ, Worthley LI "Adverse haemodynamic effects of sodium bicarbonate in metabolic acidosis." [Ref], Experimentally, the administration of intravenous hypertonic sodium bicarbonate has been associated with increased serum osmolality, decreased ionized serum calcium (which is associated with decreased myocardial contractility), and peripheral vasodilation. EH&S Blog Health & Safety Safety with Sodium Bicarbonate, 222 Merchandise Mart Plaza Individual should be removed from exposure and immediately moved to an area with fresh air. Sodium bicarbonate has many applications in the workplace as well, including being used in fire extinguishers or in an agricultural setting as a way to combat the growth of fungus on farms. Get medical attention. Managing Exposure to Sodium Bicarbonate Sodium bicarbonate should be stored in a tightly closed container and placed in a cool, dry, well-ventilated area. ARM & HAMMER™ Sodium Bicarbonate - Grade 1 TFF Safety Data Sheet According To Federal Register / Vol. ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of carbon monoxide, carbon dioxide and sodium oxides. It is a component of the mineral natronand is f… This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 7. South Med J 73 (1980): 1339-42,1348, 2. Sodium Bicarbonate Powder 10. Cleaning Products & Solvents. Okada H, Inoue T, Takahira S, Sugahara S, Nakamoto H, Suzuki H "Daytime hypertension, sleep apnea and metabolic alkalosis in a haemodialysis patient - the result of sodium bicarbonate abuse." (NTP, 1992) Material Safety Data Sheet Sodium bicarbonate MSDS Section 1: Chemical Product and Company Identification Product Name: Sodium bicarbonate Catalog Codes: SLS3241, SLS2446, SLS3868 CAS#: 144-55-8 RTECS: VZ0950000 TSCA: TSCA 8(b) inventory: Sodium bicarbonate CI#: Not available. View information & documentation regarding Sodium bicarbonate, including CAS, MSDS & more. Even though sodium bicarbonate is relatively safe compared to other chemicals in the workplace, as with any chemical, all unnecessary exposure should be avoided. Wu DJ, Mifune J, Taga K, Hifumi S, Takahashi Y, Yamashida S, Nishioka S, Murakami T, Tanaka T "Anginal attack following a sodium bicarbonate and hydrocortisone injection." Applies to: Congestive Heart … [Ref], As an antacid, sodium bicarbonate, especially after excess food or liquid, can cause excess gas release (when combined with gastric acid). Without adequate ventilation, worsened systemic acidosis could develop. Sodum bicarbonate has two pKas, 6.4 and 10.3. 58 / Monday, March 26, 2012 / Rules And Regulations 03/12/2015 EN (English US) 2/5 Ingestion: Rinse mouth. Seek medical attention immediately if any breathing difficulty occurs. Ann Arbor, MI 48108 Astra USA, Westborough, MA. In this rare circumstance, the serum potassium may be elevated. Chronic ingestion of bicarbonate may rarely cause intravascular volume expansion with resultant hyporeninemia and hypoaldosteronemia. Lazebnik N, Iellin A, Michowitz M "Spontaneous rupture of the normal stomach after sodium bicarbonate ingestion." 3 Effective date : 01.06.2015 Page 2 of 6 Sodium Bicarbonate, Reagent Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - www.gsmsds.com CAS 144-55-8 Sodium Bicarbonate 100 % Percentages are by weight SECTION 4 : First aid measures Description of first aid measures [Ref], 1. Ann Intern Med 101 (1984): 649-50, 22. Sodium bicarbonate is a white solid that is crystalline, but often appears as a fine powder. Keep away from acids, excessive heat and moisture. T2E 6J7 1.866.620.6034 Safety Data Sheet Sodium Bicarbonate Document No. Cellulitis, tissue necrosis, ulceration, or skin sloughing have possibly been the result of extravasation. Rare cases of sodium bicarbonate abuse have been associated with features of Munchausen syndrome. J Crit Care 9 (1994): 255-61, 18. © Copyright 2019 VelocityEHS. If improperly handled, or in the event of accidental exposure, sodium carbonate can pose several hazards to your health and safety. Mastrangelo MR, Moore EW "Spontaneous rupture of the stomach in a healthy adult man after sodium bicarbonate ingestion." Eyes Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Avoid dust formation. Since sodium bicarbonate is most-often seen in a powder-like state, chemical safety goggles should be worn and an area to wash eyes and skin should be located in the work area. 4) Ingestion May be harmful if swallowed (H303). It’s odorless, non-combustible and reacts with acids to release carbon dioxide gas and heat. Links with this icon indicate that you are leaving the CDC website.. M-D6-010 Oster JR, Perez GO, Rosen MS "Hyporeninemic hypoaldosteronism after chronic sodium bicarbonate abuse." Sodium bicarbonate is a common ingredient in cleaning, detergent and degreasing products. Heartburn Relief. It's a slight skin and eye irritant, and can cause increased thirst. OSHA Vacated PELs: Sodium bicarbonate: No OSHA Vacated PELs are listed for this chemical. Jpn Heart J 31 (1990): 109-13, 4. Oakville, ON L6J 3J3 The traditional Solvay process is utilized in most parts of the world, with the exception of the U.S., where all production is based on the minerals which contain sodium carbonate. In this rare circumstance, the serum potassium may be elevated. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations … Protective gloves and clothing should be worn. Linford SM, James HD "Sodium bicarbonate abuse: a case report." Side Effects & Safety When taken by mouth: Sodium bicarbonate is LIKELY SAFE when taken appropriately, short-term. Page 5 of 5 MSDS - SODIUM BICARBONATE 16. Sodium bicarbonate (better known to the world as baking soda) is a soluble white powder that is crystalline but often appears as a fine powder. Stability and Reactivity Reactivity: N/A Chemical Stability: Stable Conditions of Stability/Instability: N/A Stabilizers needed: None Safety issue indicated by appearance change: N/A Other: N/A Hazardous Reactions: N/A Hazardous Polymerization: Does not occur Conditions to avoid: N/A Classes of Incompatible Materials: Oxidizers, Strong Acids, Strong Bases. Toll free: 1.888.362.2007, VelocityEHS | Humantech First-aid measures Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Sodium hydrogen carbonate CAS 144-55-8 for analysis EMSURE® ACS,Reag.Ph Eur - Find MSDS or SDS, a COA, data sheets and more information. Sodium bicarbonate is broadly used as a physiological buffer in cell culture applications. Potential Health Hazards from Sodium Bicarbonate. Application [Ref], Renal side effects have rarely included "False proteinuria". VelocityEHS®, MSDSonline® and Humantech® are proprietary trademarks of VelocityEHS. 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